PCT/ES2016/000049 (21.04.2016). Method for diagnosing dental demineralization processes – US2018146857 (A1)
The present invention relates to a quantitative ex vivo method for the complementary diagnosis of the degree of dental demineralisation by means of Raman spectroscopy, which comprises: quantifying the intensities and areas of a plurality of Stoke bands of a spectrum; and defining and calculating indices that result from dividing the areas of certain bands of interest. The diagnosis is determined by the proximity of the values of the indices to values previously obtained for the normal pattern of dental mineralisation established by analysing healthy dental parts. This method provides a complementary biomedical technique for performing quantitative ex vivo analysis of the degree of dental demineralisation on dental tissue remains extracted by medical prescription, and the information obtained can facilitate the prescription of suitable treatment to reduce or prevent said demineralisation.
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E13380041 (30.09.2013), ES2565637 T3 (06.04.2016). Method of obtention of faceted fluorapatite nanocrystals
The invention discloses the obtention of fluora-patite (FA) nanocrystals from enameloid sections of shark teeth for application as bone filler material in or-thopedical surgery, enamel regeneration and other den-tal and maxillofacial treatments in the medical field.
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P201500293 (27.04.2015), ES2587883 A1 (27.10.2016). Method for diagnosing dental demineralization processes
The present invention relates to a quantitative ex vivo method for the complementary diagnosis of the degree of dental demineralisation by means of Raman spectroscopy, which comprises: quantifying the intensities and areas of a plurality of Stoke bands of a spectrum; and defining and calculating indices that result from dividing the areas of certain bands of interest. The diagnosis is determined by the proximity of the values of the indices to values previously obtained for the normal pattern of dental mineralisation established by analysing healthy dental parts. This method provides a complementary biomedical technique for performing quantitative ex vivo analysis of the degree of dental demineralisation on dental tissue remains extracted by medical prescription, and the information obtained can facilitate the prescription of suitable treatment to reduce or prevent said demineralisation.
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PCT/ES2014/000212 (11.12.2014). Method for diagnosing cancers of the oral and pharyngeal mucosa
The present invention relates to a method for diagnosing cancers in the oral and pharyngeal cavity by using Raman spectroscopy, comprising quantifying the intensities and areas of a variety of Stokes spectrum bands and the definition and calculation index resulting from dividing the areas of two different bands. The diagnosis is determined by proximity of the values ​​of these indices to the values ​​previously obtained in normal cells and cancer cells.
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P201301151 (13.12.2013), ES2543848 A1 (24.08.2015). Method for diagnosing cancers of the oral and pharyngeal mucosa
The present invention relates to a method for diagnosing cancers in the oral and pharyngeal cavity by using Raman spectroscopy, comprising quantifying the intensities and areas of a variety of Stokes spectrum bands and the definition and calculation index resulting from dividing the areas of two different bands. The diagnosis is determined by proximity of the values ​​of these indices to the values ​​previously obtained in normal cells and cancer cells.
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 P201100999 (13.09.2011), ES2399261 A1 (27.03.2013). Synthetic coating of bone implant.
The invention describes the incorporation of selenium in hydroxyapatite coatings for bone implants. Selenium gives the structure a greater resemblance to bone tissue and greater biochemical functionality with respect to the implants of the technique based on calcium phosphates with other minority elements. It achieves an improvement in osseointegration inhibiting the proliferation of osteoclasts and promoting healthy osteoblasts, and also has antibacterial and anticancer properties. .
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P201000898 (07.07.2010), ES2394837 A1 (06.02.2013). Method for the removal of wax into porous rocks of historic monols.
Alternative embodiments and possible alternatives to the disclosed method include methods of cleaning wax, substantially equivalent impurities, and other contaminants from the porous rocks in historical monols and of thecnical works using non destructive means. According to a specific embodiment of the disclosed method, the removal of contaminants from the porous rocks by laser technology comprises the following steps: (a) the identification of the regions with a contaminant in the medium of porous rock; (b) the characterization of the contaminant in the medium of porous rock; (c) the invention relates to the exposure of the contaminant in the medium of porous rock to the irradiation of plants the invention is characterised in that it is characterised in that it is intended for the purpose of the invention to be limited in the scope of the invention a laser beam characterized by a wavelength, a pulse duration or a pulse duration , A repeating frequency, and a laser energy density determined and optimized for a given porous pollutant rock system and (d) evaluating the results of the cleaning by quantifying the thickness of the remaining contaminant.
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P200602817 (07.11.2006), ES2304207 A1 (16.09.2008) Applicant: UNIVERSIDAD DE SEVILLA. Obtaining biomorphic ceramicas of SiC from resources marine.
This invention deals with the obtaining of biomorphic silicon carbide (SiC) ceramic materials from precursors of marine origin, such as algae, plants or sponges. With this it is possible to obtain porous materials with a wide range of microstructures offered by the marine environment since it has a great biodiversity, until now unexplored in this field of application. The manufacturing method consists of the following stages: A) selection and drying of the marine precursor; B) controlled pyrolysis in an inert atmosphere; C) molding of the carbonaceous preform; D) infiltration with silicon in vacuum; E) obtaining SiC ceramics.
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P200203052 (20.12.2002), ES2214956 A1 (16.09.2004), Biocompatible Material.
The object of the present invention is a new biocompatible material to be used in the manufacture of implants, prostheses or biomedical devices, and that is produced using as material of ceramic support biomorphic SiC with bioactive glass coating deposited by laser ablation down.
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PCT/ES1997/000269 (10.11.1997), BONE SYSTEM. Method for improving the osteointegration of osseous fixing implants . – US6339913 (B1)
The osteointegration of osseous fixing implants may be improved through a series of surface treatments. Said treatments comprise a cleaning and passivation process, the application of a coating in the system Ca-P-H-O-C through the laser ablation technique and a sterilisation process by irradiation. The flexibility of this method provides for the control of physico-chemical properties of the obtained surface in order to match said properties with those of the bone in which the implant will be placed.
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P9602439 (12.11.1996) ES2113834 A1 (01.06.1998), Solicitante: BONE SYSTEM. Method for improving the osteointegration of osseous fixing implants.
The osteointegration of osseous fixing implants may be improved through a series of surface treatments. Said treatments comprise a cleaning and passivation process, the application of a coating in the system Ca-P-H-O-C through the laser ablation technique and a sterilisation process by irradiation. The flexibility of this method provides for the control of physico-chemical properties of the obtained surface in order to match said properties with those of the bone in which the implant will be placed.
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P9700026 (27.12.1996) ES2138895 A1 (16.01.2000), ​SI/SIO2 Double coatings produced by Laser.
​Si/SiO2 double coatings produced by laser. Silicon/silicon oxide coatings can be applied on different materials and components by means of a method based on Chemical Deposition from laser induced Vapor (LCVD). This method makes use of an ArF excimer laser to radiate different mixtures of precursor gases introduced into a reaction chamber in which a high vacuum has previously been made. ​The flexibility of this method allows for controlling the physical chemical properties and the thickness of the coatings, being of special application in the protection of metallic materials against the attack of external agents, fundamentally when said components are subjected to high temperatures and very aggressive atmospheres.
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PCT/ES1994/000058 (09.06.1994), Ceramic coatings produced by the use of a silent discharge excimer lamp. — WO9429493 (A2); WO9429493 (A3)
Ceramic coatings within the system Si-O-N-C, may be applied to various materials and components by means of a method based on the lamp-induced chemical vapor deposition (Lamp-CVD). The flexibility of this method makes possible the control of the physic-chemical properties of the coatings which apply specially to the fields of microelectronics, optoelectronics, solar cells and protection of materials.
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P9301284 (10.06.1993) ES2067410 A1 (16.03.1995), Silicon nitride coatings produced by silent discharge excimer lamp.
Silicon nitride coatings can be applied to different materials and components by means of a method deposition Based on Chemical Vapor from Induced Lamp (LAMP-CVD). The flexibility of this method makes it possible physico-chemical properties of the coatings, being of special application in the fields of microelectronics, optoelectronics, solar cells and material protection.
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P9300890 (27.04.1993) ES2068133 A1 (01.04.1995), Silicon oxide coatings produced by means of a silent-discharge excimer lamp for the protection of metal elements
Silicon oxide coatings can be applied to metal materials and components by means of a method based on lamp-induced chemical vapour deposition (Lamp-CVD). These coatings give them protection against corrosion, oxidation, sulphuration and carburization, essentially when said metal components or materials are subjected to high temperatures and very aggressive atmospheres. By means of this method it is possible to protect metal components (made, for example, with stainless steels, carbon steels or Ni alloys) used in heat exchangers, furnaces or turbines.
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P9201060 (22.05.1992) ES2046948 A1 (01.02.1994), Ceramic coatings produced by laser for the protection of metallic elements.
Materials and components metallic can be coated with a ceramic material, silicon oxide by means of a method based on the depositionfrom chemical vapor induced laser (LCVD). This ceramic coating gives them protection against corrosion, oxidation, sulphidation and carburisation, mainly when such metallic material components or are subject to high temperatures and atmosferas very aggressive. By this method may be protected metal components (made, for example, Stainless steel, carbon steel or alloy Ni) for use in heat exchangers, boilers or turbines.
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